Mila kula anganggit sêrat punika, supados kawontênanipun têtuwuhan tuwin oyod-oyodan ingkang kathah paedahipun, sagêda kasumêrêpan ing akathah, dene ingkang kula wastani têtuwuhan wau kathah ingkang kaanggêp rêrungkudan kemawon, inggih lêrês ngantos sapriki jampi Jawi sampun kangge, ananging kadospundi kanggenipun sarta rekanipun angangge jampi wau, makatên ugi namanipun tanêman ingkang kangge jampi asring kadamêl wados, mila pangupadosipun katêrangan bab jampi-jampi Jawi asring botên sagêd kadugèn, sarta kawruh bab jampi-jampi wau asring ical sarêng ingkang gadhah kawruh wau tilar ing donya, awit kawruhipun dipun damêl wados.

Selasa, 30 Agustus 2011

SENNAE FOLIUM 5 - Sennoside 1

SENNAE FOLIUM 5 - Sennoside 1


Sennoside


Sennoside A

Sennoside B

Sennoside B

Common Name

Sennoside B

Description

Sennoside B is an anthranoid. Anthranoid derivatives are used all over the world as a treatment for constipation. These compounds are present in several drugs of plant origin, especially as O- or C-glycosides. Besides featuring different substituents, the aglycone might consist of an anthraquinone, an anthrone or a dianthrone. So far, detailed information concerning their metabolism and pharmacokinetic characteristics is available only in a few cases. The best characterized compounds are sennoside, a dianthrone O-glycoside present in senna leaves and senna pods, and its aglycone (rhein anthrone). After oral administration, sennoside is degraded only in the lower parts of the gastrointestinal tract, releasing its active metabolite rhein anthrone. (PMID: 8234447)

Synonyms

  1. Sennoside B (6CI,7CI,8CI)
  2. 5,5'-bis(b-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-10,10'-dioxo-[9,9'-Bianthracene]-2,2'-dicarboxylic acid
  3. 5,5'-bis(beta-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-10,10'-dioxo-[9,9'-Bianthracene]-2,2'-dicarboxylic acid
  4. 5,5'-bis(b-delta-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-10,10'-dioxo-[9,9'-Bianthracene]-2,2'-dicarboxylic acid
  5. 5,5'-bis(beta-delta-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-10,10'-dioxo-[9,9'-Bianthracene]-2,2'-dicarboxylic acid

Chemical IUPAC Name

(9S)-9-[(9R)-2-carboxy-4-hydroxy-10-oxo-5-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracen-9-yl]-4-hydroxy-10-oxo-5-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracene-2-carboxylic acid

Chemical Formula

C42H38O20 Chemical

Structure

http://hmdb.ca/labm/servlet/labm.mlims.show?ctrl=chemical_structure&hmdb_id=HMDB02783

Sennoside B - Calcium salt

Sennoside C

Sennoside D




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